HOUSTON — Ryan O’Hearn, who went to high school in northern Texas and played college ball at nearby Sam Houston State, looked right at home on Tuesday night at Minute Maid Park, especially during his second at-bat in the Royals’ 12-2 rout of the Astros.

O’Hearn, who grew up four hours north of Houston in Frisco, hit the first grand slam of his career in the third inning off Houston starter Collin McHugh, putting the Royals ahead, 6-0.

According to Statcast, O’Hearn’s slam left his bat at 107 mph and traveled a projected 373 feet, landing in the right-field stands and capping a five-run inning that nearly resulted in the Royals collectively hitting for the cycle. They were shy a single to go with Whit Merrifield’s triple and Adalberto Mondesi’s double.

Merrifield, who was a double shy of the cycle, extended the Royals’ lead to 12-1 with a grand slam in the top of the seventh — his fourth hit of the game.

The last time two Royals hit grand slams in the same game was Aug. 13, 2004, at Oakland, off the bats of Abraham Nunez and John Buck.